Current and Recent Funding

Recent Publications

  • Ward, K.T., Williams, A.P.L.; Dennison, A.L., Aamir, L., Allen, D.L., Chavez-Arellano, B., Marchlewski, T.A., Zappia, M.L., Wolfe, A.L.,* Steed, P.R.* (2025)“Quinoine ATP synthase inhibitors with activity against multidrug resistant Acinetobacter baumannii and Pseudomonas aeruginosa.” Chem. Med. Chem. e202400952.
  • Ward, K.T., Williams, A.P.L., Blair, C., Chaterjee, A., Karthikeyan, A., Roper, A., Kellogg, C.N., Steed, P.R.,* and Wolfe, A.W.* (2023) “Amine Basicity Drives Pseudomonas aeruginosa ATP synthase Inhibition and Antibacterial Activity of Quinoline Analogs.” ACS Med. Chem. Lett. 15, 149-155.
  • Fraunfelter, V.M., Pugh, B.A.,Williams, A.P.L., Ward, K.T., Jackson, D.O., Austin, M., Ciprich, J.F., Dippy, L., Dunford, J., Edwards, G.N., Glass, E., Handy, K.M.,Kellogg, C.N.,Llewellyn,K., Nyberg, K.Q., Shepard, S.J.,Thomas, C., Wolfe, A.L.,* and Steed, PR.* (2023) “Quinoline compounds targeting the c-ring of ATP synthase inhibit drug-resistant Pseudomonas aeruginosa.” ACS Infectious Diseases. 9, 2448-2456.
  • Shrestha, R.K., Founds, M.W., Rothrock, M.M., Shepard, S.J., Defnet, A.E., and Steed, P.R. (2023) “Mutational analysis of a conserved positive charge in the c-ring of E. coli ATP synthase.” BBA-Bioenergetics. 1864, 148962
  • Ciprich, J., Buckhalt, A.J.E., Carroll, L.L., Chen, D., Defiglia, S.A., McConnell, R.S., Parmar, D.J., Pistor, O.L., Rao, A.B., Rubin, M.L., Volk, G.E., Steed, P.R., and Wolfe, A.L. (2022) “Synthesis and evaluation of Pseudomonas aeruginosa ATP synthase inhibitors.” ACS Omega. 7, 28434-28444.